米索前列醇用于人工流产221例扩张宫颈临床研究

目的:探讨米索前列醇在人工流产中对扩张宫颈的效果。方法:收治自愿流产患者221例,随机分成对照组和观察组分别为100例和121例,观察组口服米索前列醇400μg组与对照组不服药物,观察宫颈扩张及手术情况。结果:宫颈扩张及手术情况:观察组121例中宫颈松驰101例(83.5%),较松驰19例(15.7%),无困难患者发生;对照组较松驰5例(5.0%),95例困难。手术时间:观察组21.3±8.6分钟,对照组手术时间39.3±10.2分钟;术中出血:观察组14.9±5.3ml,对照组22.5±10.9ml,两组比较差异有显著性(P<0.05)。结论:米索前列醇可以有效扩张宫颈,减少出血,缩短手术时间,减少痛苦,患者易接受等优点。

Objective：To explore the misopr- ostol abortion cervical dilatation effect. Methods：Voluntary abortion patients in our cinic in April 2010 to December 2011 221 cases were randomly divided into control group and observation group were 100 cases and 121 cases of observation group oral mi- soprostol 4001~g group The control group was dissatisfied with the drugs, observation of cervical dilatation and surgical conditions. Results： 121 cases of cervical dilata- tion and surgical conditions： observation group in cervical relaxation of 101 cases, accounting for 83.5% , representing a relaxa- tion of the 19 cases,accounting for 15.7%, no difficult patients ; the control group compared with relaxation of five cases, accounting for 5.0% 95 cases of difficulty. Surgery： observation group 21.3 ± 8.6min, the control group, operative time 39. 3± 10. 2rain, blood loss： the observation group 14. 9± 5.3ml of the control group 22. 5 ± 10. 9ml inthe two groups there was a significant difference （ P 〈 0. 05 ）. Conclusion： Misoprostol can be effective dilatation of the cervix, reducing bleeding, shorter operative time, re duce pain, patients tend to accept the advan tages worthy of promotion.