水团花化学成分的研究

Studies on the Chemical Constituents of Adina pilulifera

目的:研究茜草科植物水团花Adina pilulifera根部的化学成分。方法:采用硅胶柱色谱、SephadexLH-20凝胶柱色谱等柱层析方法进行分离纯化,经波谱分析和化学方法进行结构鉴定。结果:从水团花根部分离得到12个化合物,分别鉴定为quinovic acid(1),quinovic acid3-β-D-glucopyranoside(2),quinovic acid3-β-D-glucopyranoside(28→1)-β-D-glucopyranoside(3),quinovic acid3-β-D-glucopyranosyl-(1→3)-rhamnopyranoside(4),芦荟大黄素(5),sweroside(6),loganin(7),noreugenin(8),undulatoside B(9),5,7-dihydroxy-2-methyl-chromone7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside(10),β-谷甾醇(11)和胡萝卜苷(12)。结论:化合物4、5、6、11和12为首次从水团花植物中分离得到。

Objective： To study the chemical constituents of the root of Adina pilulifera. Methods： The compounds isolation and purification used silica gel column, Sephadex LH-20 column Chromatography, and their structure identification used spectral and chemical methods. Results： Twelve compounds were isolated and identified. There are quinovic acid （ 1 ）, quinovic acid 3-β-D-glucopyranoside （ 2 ）, quinovic acid 3-β-D- glucopyranoside （28→ 1 ） -β-D-glucopyranoside （3）, quinovic acid 3-β-D-glucopyranosyl-（ 1→3 ） -rhamnopyranoside （4）, aloe-emodin （5）, sweroside （6）, loganin （7）, noreugenin （8）, undulatoside S （9）, 5,7-dihydroxy-2- methyl-chromone 7-O- β-D-apiofuranosyl-（ 1 →6 ） -/3-D-glucopyranoside （ 10 ）, β-sterol （ 11 ） and daucosterol （ 12 ）. Conclusion： It is the first time that Compound 4, 5, 6, 11 and 12 isolated from A. pilulifera.