低温中药灌肠预防宫颈癌患者放射性直肠损伤的效果

Effect of low temperature enema with Chinese herbal drugs on preventing radioactive rectum damage in patients with cervical cancer

目的探讨低温中药灌肠预防宫颈癌患者放射治疗所致直肠损伤的效果。方法将100例采取后装放射治疗的宫颈癌患者随机分为试验组和对照组,两组均采用后装放射治疗常规护理方法。试验组除常规护理外,在施用器放置后,用导尿管连接微量输液泵直肠给药降温,微泵匀速推注4～6℃自制中药10～15ml,后装放射治疗后行上述成分中药常规方法保留灌肠,1次/d,连续3d。观察后装放射治疗5次后3d内、放疗结束后3个月、6个月两组患者发生放射性直肠损伤的情况。结果试验组后装放射治疗5次后3d内,1、2级直肠反应发生率均低于对照组;后装放射治疗结束后3个月、6个月,试验组直肠损伤的发生率及损伤的程度低于对照组,差异均有统计学意义(P=0.000)。结论低温中药灌肠可降低宫颈癌患者行后装放射治疗所致的放射性直肠反应。

Objective To examine the effect of low temperature enema with Chinese herbal drugs on preventing radioactive rectum damage in patients with cervical cancer.Methods One hundred patients with cervical cancer treated by after-loading radiology therapy were randomly divided into two groups.In addition to routine nursing care,the patients in the experimental group received low-temperature enema with Chinese herbal drugs once a day for three days.The radioactive rectum damage was compared between the two groups within three days,three months and six months after therapy.Results The incidence of grade-1 and grade-2 radioactive rectum damage in the experimental group within three days after therapy was significantly lower than that of control group.The incidence and degree of radioactive rectum damage in the experimental group at three months and six months after therapy were significantly lower than that of control group（P=0.000）.Conclusions Low-temperature enema with Chinese herbal drugs can effectively prevent radioactive rectum damage in patients with cervical cancer treated by after-loading therapy.