逍遥丸治疗儿童肠易激综合征随机对照研究

Randomized Controlled Study of Xiaoyao Pill Treating Irritable Bowel Syndrome in Children

目的:观察逍遥丸治疗儿童肠易激综合征的临床疗效。方法:观察组32例采用逍遥丸治疗,与空白对照组31例相比较,观察8周。结果:观察组和对照组的总有效率分别为84.38%,38.71%(P<0.01);逍遥丸在改善腹痛、腹胀及大便次数增多、排便不尽感及大便性状等方面均优于对照组,差异具有显著性意义;而在改善黏液便方面,两组差异不具显著性意义(P>0.05);逍遥丸能明显改善患儿肝郁脾虚证候,治疗前后证候积分比较具有显著性差异。结论:逍遥丸对于儿童肠易激综合征具有较好的临床疗效,并能有效改善肠易激综合征患者症状。

To observe the clinical effect of Xiaoyao Pill treating the irritable bowel syndrome in children. Methods ： 32 cases in treatment group received Xiaoyao Pill and 31 cases of the control group were observed for 8 weeks. Results ： The overall reactions rates of treatment group and the control group were 84.38% and 38.71% respectively （P〈0.01）.Xiaoyao Pill treatment group was better than the control group in several aspects, such as improving the symptom of abdominal pain and abdominal distension ; for diarrhea there were significant statistical differences between two groups. But for improving the symptom of mucosa, differences between the two groups had no significance （ P〉0.05 ）; Xiaoyao Pill can obviously improve the syndrome of liverdepression and spleen-deficiency, syndrome scores of groups showed significant difference in comparison of before and after treatment. Conclusion ： Xiaoyao Pill treating irritable bowel syndrome in children has good effects, and can improve the symptoms of the irritable bowel syndrome in children effectively.