舌下含服粉尘螨滴剂治疗变应性鼻炎疗效观察

Observition on the effect of the dust mite sublingual immunotherapy for allergic rhinitis

目的:观察舌下免疫治疗粉尘螨性变应性鼻炎的疗效。方法:记录188例对粉尘螨过敏的变应性鼻炎患者舌下免疫治疗前及治疗后6个月、12个月的症状评分和VAS评分,比较其治疗效果。结果:188例患者治疗后6个月症状已有明显改善,差异有统计学意义(P<0.01);治疗后12个月喷嚏、流涕的症状改善更显著(P<0.01)。结论:舌下脱敏治疗粉尘螨性变应性鼻炎是一种安全、有效的针对病因的治疗方法,值得推广。

Objective：To evaluate the cilinical effect of sublingual immunotherapy with dust mite for allergic rhinitis. Method：The symptom score of 188 patients with dust mite allergic rhinitis were recorded before and after treatment for six months,a year,and compare the treatment effects. Result： Symptom scores of 188 patients were decreased after treatment than before, the symptoms of treatment were improved significantly after six months, symptoms were improved more significantly after one year, the difference was significant（ P〈0. 01）. Conclusion： Sublingual immunotherapy with dust mite is a safe and effective treatment for allergic rhinitis, and it is worthy of promotion.