正畸支抗种植体骨整合与稳定性的实验研究

An experimental investigation between osseointegration and stability of implants used as orthodontic anchorage in dogs

目的 考察正畸支抗种植体的骨整合与稳定性以及二者之间的关系。方法 将HA涂层钛种植体、钛浆喷涂钛种植体、未涂层钛种植体植入狗股骨 ,愈合期后施加 1 96N正畸力 2个月。测量施力后种植体的位置变化和种植体—骨界面的剪切结合强度 ,用扫描电镜观察界面。结果 3种种植体位移分别为 (- 0 5 0± 1 78)mm、(- 0 0 5± 1 76 )mm、(0 2 9± 1 77)mm ,统计学分析结果显示 ,还不能认为 3种种植体出现移动。 3种种植体—骨界面的剪切结合强度分别是 (2 88± 0 5 5 )MPa、(1 89± 0 81)MPa和 (2 14± 0 49)MPa。HA涂层种植体与骨紧密结合 ,其界面结合强度最高 ;另外 2种种植体与骨的结合强度差异无显著性。结论 虽然HA涂层种植体与骨结合最牢固 ,但 3种种植体—骨界面均可形成骨整合 ,在常规正畸力作用下不会发生明显移动。本项研究结果表明 ,种植体可用作短期的正畸支抗。

Objective To investigate the relation between osseointegration and stability of three kinds of implants used as orthodontic anchorage in dogs Methods HA coated, titanium coated, and uncoated titanium implants were inserted into each femur of two dogs After heal period of three months, the orthodontic force of 200 g was applied by means of Ni Ti springs, which were connected to the two adjacent implants, for two months The position change of implants was measured and calculated The shear bond strength of interface between implant and bone was measured with push test The interface was observed with scanning electronic microscope Results The distance changes of HA coated, T coated and uncoated groups were –(-0 50±1 78) mm, (-0 05±1 76) mm and (0 29±1 77) mm, respectively, which showed no statistical difference The shear strength values were (2 88±0 55)MPa, (1 89±0 81) MPa and (2 14±0 49) MPa, respectively HA coated implant contacted with bone closely and the bond strength was the highest. The other two implants were found no significant difference in bond strength. Conclusion The osseointegration was found at the interface among all three kinds of implants and bone and no displacement was found during application of clinical orthodontic force