摘要
目的:探讨卡前列素氨丁三醇防治剖宫产术中、术后出血的临床疗效。方法:选择有出血高危因素行剖宫产术的产妇120例,分成研究组及对照组,每组60例。两组均在胎儿娩出后常规静脉滴注催产素的基础上,研究组于宫体注射卡前列素氨丁三醇250μg,对照组予卡孕栓1.0mg舌下含服,比较两组术中出血量、产后2h及产后2~24h内的出血量及两组产后出血率。比较两组患者用药前及用药后生命体征变化。结果:研究组术中出血量、产后2h出血量、产后2~24h出血量均少于对照组,差异均有统计学意义(P<0.05),研究组产后出血率低于对照组,差异有统计学意义(P<0.05);两组用药前、后生命体征变化相近,差异无统计学意义(P>0.05)。结论:卡前列素氨丁三醇可有效防治有出血高危因素产妇剖宫产术中、术后出血,快速方便,效果确切,不良反应少。
differences between two groups on intraoperative blood loss, postpartum hemorrhage in 2 h and 2 -24 h (P〈0.05); And the incidence rate of postpartum hemorrhage in study group was less than that in control group (P 〈 0.05). There were no significant differences on the change of vital signs before and after treatment (P〈0.05) CONCLUSION: It was effective, rapid and con- venient to use carboprost tromethamine for the prevention and treatment in high hemorrhagic risk fators of PPH during CS with less adverse reaction
出处
《中国临床药理学与治疗学》
CAS
CSCD
2012年第3期326-330,共5页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
卡前列素氨丁三醇
剖宫产
产后出血
高危孕产妇
Carboprost tromethamine
sarean section
Postpartum hemorrhagerisk parturient CeHigh