温胃散合奥美拉唑治疗消化性溃疡临床研究

Clinical Study on Peptic Ulcer Treated by Warming Stomach Powder Combined with Omeprazole

目的:探讨中西医结合治疗消化性溃疡的临床疗效。方法:将纤维胃镜确诊的216例消化性溃疡患者随机分为中西医结合组与西医治疗组,中西医治疗组108例,用温胃散(方药组成:黄芪120 g,莪术45 g,党参90 g,山药90 g,鸡内金60 g,刺猬皮60 g,蒲黄60 g,五灵脂60 g,炮穿山甲45 g,玉蝴蝶45 g,凤凰衣45 g,甘草45 g)合奥美拉唑治疗;西医治疗组108例选用奥美拉唑治疗;合并幽门螺杆菌(HP)感染者加克拉霉素治疗,治疗45 d,观察疗效。结果:中西医结合组有效率96.3%,HP感染清除率89.7%,奥美拉唑组有效率82.3%,HP感染清除率73.7%,两组比较差异具有统计学意义(P<0.05)。结论:温胃散合奥美拉唑治疗消化性溃疡效果优于单纯西药治疗组。

Objective：To probe into the clinical effects of the integration of TCM and Western medicine in the treatment of peptic ulcer.Methods：216 patients of peptic ulcer diagnosed by fibergastroscope were randomly divided into the integration of TCM and Western medicine treatment group and the Western medicine treatment group.108 patients in the integration of TCM and Western medicine treatment group were treated by Warming Stomach Powder（Recipe components：Astragalus 120 g,Curcuma 45 g,Codonopsis 90 g,Chinese yam 90 g,chicken′s gizzardskin 60 g,the hedgehog skin 60 g,cattail pollen 60 g,trogopterus dung 60 g,the prepared pangolin 45 g,jade butterflies 45 g,membrane of hen egg 45 g,licorice 45 g.）combined with Omeprazole;others in the Western medicine treatment group were given Omeprazole,and Clarithromycin would be added for use if patients were infected by HP.After a treatment of 45 days,curative effects were analyzed.Results：Curative rates in the integration of TCM and Western medicine treatment group and the Western medicine treatment group were 96.3% and 82.3% respectively,and clearance rate of HP infection in two groups were 89.7% and 73.7% respectively.Difference in both groups had statistic significance（P0.05）.Conclusion：Warming Stomach Powder combined with Omeprazole has better curative effects on the treatment of peptic ulcer,and is superior to the single use of western medicine.