摘要
目的:探讨血清癌胚抗原(CEA),糖类抗原72-4(CA72-4),糖类抗原19-9(CA19-9)水平在贲门癌及胃窦癌诊断价值。方法:整理河南省肿瘤医院普外科2009年3月至2010年11月的236例胃癌患者CEA、CA72-4、CA19-9的检测结果,并以200例健康体检病人为正常对照组进行分析。结果:贲门癌组血清CEA的阳性率明显高于CA72-4,CA19-9。含CEA的两项联合检测可使检测的阳性率明显提高,且两种联合检测有明显差异,3者联合检测阳性率可达66.7%。胃窦癌组3种血清肿瘤标志物单独检测时的阳性率无明显差异,联合检测CEA和CA72-4或CA19-9可使检测的阳性率有所提高,3者联合检测阳性率可达57.4%。结论:血清CEA、CA72-4、CA19-9水平在贲门癌及胃窦癌的诊断有一定意义,阳性率与肿瘤的部位有关,联检可提高胃癌尤其是贲门癌的诊断阳性率。
Objective： To discuss prognostic value of serum carcinoembryonic antigen（CEA）,carbohydrate antigen（CA）72-4 and CA 19-9 levels in cardia cancer and distal gastric cancer. Methods： 236 gastric cancer patients were analysed through retrospective analysis,whom from march 2009 to november 2010 in general surgery department of henan tumor hospital,and 200 healthy subjects as control group. Results： The positive rate of serum CEA is significant higher than the others. Including CEA could improve Diagnosis of positive,there is significant deviation between two combinations,while positive rate in combination of three serum markers 66.7%.There is no significant deviation of serum CEA,CA72-4,CA19-9 in distal gastric cancer group,the combination of CEA and CA72-4 or CA19-9 could improve positive rate,while positive rate in combination of three serum markers 54.7%. Conclusion： The serum CEA,CA72-4 and CA 19-9 levels will cont-ribute to the prognosis in gastric cancer,positive rate is concerned with tumor position,while combination could improve Positie diagnosis in gastric cancer,especially in cardiac cancer.
出处
《河南医学研究》
CAS
2012年第1期42-44,共3页
Henan Medical Research
