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酮内酯类抗生素研究进展 被引量：2

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摘要 大环内酯类抗生素是以多羟基14-16元大环内酯为母体,通过内酯环上的羟基和去氧氨基糖缩合而成的碱性苷化合物。1952年,第一个大环内酯类抗生素红霉素（Erythro-mycin,图1）被发现,但由于其化学性质不稳定,
作者 于丽佳 薛飞群 赵树春 沈晓炯 何建伟
机构地区 中国农业科学院上海兽医研究所 河北科技大学 防化研究院第四研究所
出处 《中兽医医药杂志》 2012年第2期24-29,共6页 Journal of Traditional Chinese Veterinary Medicine
基金 "十二五"农村领域国家科技计划
关键词 大环内酯类抗生素 酮内酯类 化学性质 化合物 氨基糖 红霉素 不稳定 羟基
分类号 S859.796 [农业科学—临床兽医学]
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参考文献20

  • 1姚晓英,张永信.大环内酯类抗生素的发展和研究近况[J].上海医药,2011,32(7):319-322. 被引量：15
  • 2Xu P,Liu L,Lei P S,et al.Synthesis of novel macrolidederivatives with imidazo[4,5-b]pyridinyl sulfur containedalkyl side chains and their antibacterial activity[J].Journal ofBioorganic&Medicinal Chemistry Letters,2009,19(15):4079-4083.
  • 3Putnam S D,Castanheira M,Moet G J,et al.CEM-101,anovel fluoroketolid:antimicrobial activity against a diversecollection of gram-positive and gram-negative bacteria[J].Diagnostic Microbiology and Infectious Disease,2010,66(4):303-401.
  • 4Magee T V,Ripp S L,Li B,et al.Discovery of AzetidinylKetolides for the treatment of susceptible and multidrugesistant[J].Journal of Medicinal Chemistry,2009,52(23):7446-7457.
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  • 9Takashi N,Tatsuro Y,Yukitoshi N,et al.9-Oxime-3-ketolides:Modification at the C-11,12-diol moiety andantibacterial activities against key respiratory pathogens[J].Journal of Bioorganic&Medicinal Chemistry,2005,13(21):6054-6063.
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二级参考文献14

  • 1王登旭,王二兵,彭向前.泰利霉素的药理作用及临床应用[J].中国药物与临床,2005,5(7):524-525. 被引量：7
  • 2Farrell DJ, Sader HS, Castanheira M, et al. Antimicrobial characterisation of CEM-IO1 activity against respiratory tract pathogens, including muhidrug-resistant pneumocoecal serogroup 19A isolates [ J ]. In J Antimicrob Agents, 2010, 35(6~: 537-5d3_.
  • 3刘剑,杨明.泰利霉素研究进展[C]//四川省生理科学学会第八届学术交流会暨西部地区生理学学术研讨会.四川省生理科学学会第八届学术交流会暨西部地区生理学学术研讨会论文集.四川宜宾:[出版者不详],2007:87-89.
  • 4Rospide MF, Biedenbach D J, Jones RN. Comparative antimicrobial activity of ABT-773, a novel ketolide, tested against drug-resistant Gram-positive cocci and Haemophilus intIuenzae [ J ]. In J Antimicrob Agents, 2001, 17(6): 451- 455.
  • 5Johnson CN, Benjamin WH Jr, Gray BM, et al. In vitro activity of ABT-773, telithromyein and eight other antimierobials against erythromyein-resistant Streptococcus pneumoniae respiratory isolates of children [ J ]. In J Antimierob Agents, 2001, 18(6): 531-535.
  • 6Putnam SD, Sader HS, Farrell D J, et al. Antimicrobial eharaeterisation of solithromyein (CEM-101), a novel fluoroketolide: activity against staphylococci and enterocoeei [ J ]. In J Antimicrob Agents, 2011, 37(1): 39-45.
  • 7Putnam SD, Castanheira M, Moet GJ, et al. CEM-101, a novel fluoroketolide : Antimicrobial activity against a diverse collection of Gram-positive and Gram-negative bacteria [ J ].Diagn Microb Inlet Dis, 2010, 66(4): 393-401.
  • 8Farrell D J, Castanheira M, Sader HS, et al. The in vitro evaluation of solithromycin (CEM-101) against pathogens isolated in the United States and Europe (2009) [ J ]. J Infec, 2010, 61(6): 476-483.
  • 9Jiang LJ, Or YS. Pharmacokineyics of EDP-420 after muhiple oral doses in healthy aduh vohmteers and in a bioequivalenee study[J].Antimicrob Agents Chemother, 2009, 53(8): 3218-3225.
  • 10徐林,俞雄,朱宝泉.酮内酯类抗生素的研究进展[J].中国医药工业杂志,2009,40(8):627-636. 被引量：3

共引文献14

同被引文献7

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二级引证文献2

中兽医医药杂志
2012年 第2期

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