腹腔镜下子宫动脉上行支阻断术辅助下行子宫肌瘤剔除术对卵巢功能的影响

The effect of Laparoscopic blocking ascending branch of uterine arteries in the treatment of uterine myoma on ovarian function

目的:探索腹腔镜下子宫动脉上行支阻断辅助行子宫肌瘤剔除术对卵巢功能的影响。方法:选择2008年1月～2011年4月就诊的71例子宫肌瘤患者,机械抽样随机将其中24例分为Ⅰ组,采取上行支阻断辅助术式;余者47例分为Ⅱ组,采取常规术式。对照分析Ⅰ组和Ⅱ组患者手术前后不同卵巢功能者构成比、激素值、卵巢窦状卵泡数及手术时间和术中出血量。结果:Ⅰ组和Ⅱ组患者手术前卵巢功能正常者和卵巢储备功能下降者构成比差异无统计学意义(P>0.05),术后Ⅰ组和Ⅱ组患者E2、FSH、LH、FSH/LH比值及AFC数差异无统计学意义(P>0.05),Ⅱ组患者手术时间及术中出血量显著高于Ⅰ组(P<0.05)。结论:由于样本资料有限,虽然该研究结果显示腹腔镜下子宫动脉上行支阻断辅助行子宫肌瘤剔除术具有显著的优势,对卵巢功能无明显影响,但对于有生育要求的女性应该慎行。

Objective：To explore the laparoscopic blocking ascending branch of uterine arteries in the treatment of uterine myoma on ovarian function.Methods：The 71 patients with uterine fibroids were choose in our hospital from January 2008 to June 2011.Twenty-four cases of them were randomly taken as groupⅠ,and were taken up blocking auxiliary surgical teams;forty-seven cases of them were taken as group Ⅱ,and in the conventional surgical procedures.The rates of different ovarian function,hormone values,the number of ovarian antral follicles,the operation time and blood loss before and after surgery were compared between the two groups.Results：Before surgery,the rates of the patients with normal ovarian function and decreased ovarian reserve were not found significant difference between the two groups.（P0.05）.After surgery,the level of E2,FSH,LH,FSH / LH and AFC were also no significant difference between the two groups（P0.05）.But operative time and blood loss in group Ⅱ was significantly higher than group Ⅰ（P0.05）.Conclusion：Because of the limited sample data,although this study shown that laparoscopic uterine artery ascending branch block auxiliary line myomectomy has significant advantages,no significant effect on ovarian function,but it should be carefully used for the women who have the requirements of childbearing.