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急性冠状动脉综合征患者血清sCD40L与可溶性P-选择素关系及意义 被引量:2

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摘要 目的分析急性冠脉综合征(ACS)患者血清中可溶性CD40配体(sCD4OL)、可溶性P选择素(sCD4OL)水平变化及临床意义。方法选取ACS患者38例,稳定型心绞痛(SAP)患者32例及健康体检者20例,采用酶联免疫法测定其血清sCD4OL、sP-selectin水平,分析sCD4OL与sP-selectin的相关性。结果 ACS组血清sCD4OL(47.93±12.30)、sP-selectin(5340±123)水平均显著高于SAP组(2.57±1.23)、(1618±117)和对照组(2.11±0.86)、(1582±124),差异有显著性(均P<0.05),SAP组与对照组比较则差异无显著性(均P>0.05)。ACS患者血清sCD4OL与sP-selectin呈显著正相关(r=0.516,P<0.05)。结论 ACS患者血清sCD4OL和sP-selectin水平均明显升高,它们共同作用促进ACS的发生和发展。
出处 《医药论坛杂志》 2012年第1期84-85,共2页 Journal of Medical Forum
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