摘要
目的 :研究电针足三里穴对大鼠应激性胃粘膜损伤的保护作用。方法 :将 18只大鼠随机分为 3组 ,即正常对照组、模型组、电针组 ,采用束缚 冷应激胃粘膜损伤模型 ,观察电针足三里穴后胃粘膜损伤情况 ,以及胃粘膜血流量 ,血浆中肿瘤坏死因子 ,前列环素 /血栓素含量变化。结果 :电针后 ,胃粘膜血流量增加 (P <0 .0 1) ,肿瘤坏死因子和血栓素含量下降 (P <0 .0 1) ,前列环素含量增加 (P <0 .0 1)。结论 :电针足三里穴对胃粘膜损伤有保护作用 ,肿瘤坏死因子在其中是重要介质。
Objective:The protective effect of electroacupuncture (EA) on the stress gastric mucosal damage induced by constrained cold stress rats was studied.Method:18 rats were randomly divided into 3 groups,i.e.control,model and EA.A model of gastric mucosal damage induced by constrained cold stress was established.Gastric mucosal blood flow(GMBF),Gastric mucosal lesion index(LI),the contents of tumor necrosis factor(TNF),prostaglandin I 2(PGI 2),and thromboxane A 2 (TXA 2)in plasma were detected.Result:The level of GMBF(P<0.01) and PGI 2(P<0.01) in plasma increased after EA at Zusanli(ST 36) points,the contents of TNF(P<0.01) and TXA 2(P<0.01) decreased.Conclusion:EA could protect gastric mucosal damage and TNF plays a critical role in it.
出处
《安徽中医学院学报》
CAS
2000年第2期27-30,共4页
Journal of Anhui Traditional Chinese Medical College
关键词
电针疗法
足三里
应激性胃溃疡
肿瘤坏死因子
Electroacupuncture
Zusanli
Stress gastric ulcer
Tumor necrosis factor
Prostaglandin I 2
Thromboxane A 2
Gastric mucosal blood flow
