转换曲线分光光度法测定复方磺胺甲口恶唑片的含量

ASSAY OF CONPOUND SULFAMATHOXAZOL TABLETS BY TRANSFORMATIONAL CURVE SPECTROPHOTOMETRY

目的 :研究复方磺胺甲口恶唑片更简便的含量测定方法。方法 :用转换曲线分光光度法原理 ,以乙醇 - 0 .1mol·L- 1盐酸 (1∶ 1)为溶剂 ,直接测定复方磺胺甲口恶唑片中 SMZ和 TMP的含量。结果 :SMZ及 TMP的平均回收率和 RSD(n=6 )分别为 (10 0 .0± 0 .2 2 ) %和 (99.88± 0 .90 ) %。结论 :方法简便、快速。

OBJECTIVE:To study a better method for determining compound sulfamathoxazol tablets.METHODS:Samples were determined directly in MeOH 0.1 mol·L 1 (1∶1) by transformational curve spectrophotometry.RESULTS:The average recovery with RSD(n =6)were (100.0±0 22)% for SMZ,(99 88±0 90)% for TMP.CONCLUSION∶This method is simple and rapid with a high accurat. It provides a new method for determining compound sulfamathoxazol tablets.