胸部撞击伤后心脏功能变化的实验研究

Experimental study of heart dysfunction after chest impact trauma

目的 探讨胸部撞击伤后心脏功能的变化规律。 方法 采用兔胸部撞击伤模型 ,用单光子发射计算机断层照相机 (SPECT)在伤前和伤后不同时相点检测心脏功能。 结果 右心室射血分数、1 3射血分数、1 3射血率在撞击后 2 4h仍明显低于撞击前 (P <0 .0 5 ) ;左心室高峰充盈率、1 3充盈分数和 1 3充盈率在撞击后 2 4h仍明显低于撞击前 (P <0 .0 5和P <0 .0 1)。 结论 胸部撞击伤后右心室以收缩功能障碍为主 ,左心室以舒张功能障碍为主 ,采用SPECT检测心脏功能对诊断是有益的。

Objective To explore the change rules of the heart dysfunction after chest impact trauma. Methods We used the model of severe heart dysfunction after chest impact trauma in rabbits to examine the heart function in different time point with single photon-emission computed tomography. Results The ejection fraction, 1/3 ejection fraction and 1/3 ejection rate of the right ventricle were decreased 24 hours after impact ( P <0.05).The peak filling rate, 1/3 filling rate and 1/3 filling fraction of the left ventricle were decreased 24 hours after impact ( P <0.05 and P <0.01). Conclusions The expression of the left ventricular function is mainly diastolic dysfunction and slightly systolic dysfunction, and the expression of the right ventricular function is mainly systolic dysfunction and slightly diastolic dysfunction after chest impact trauma in rabbits. The single photon-emission computed tomography is helpful in diagnosis of heart dysfunction after chest impact trauma.