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高通量血液透析对血清β_2微球蛋白和C反应蛋白的影响 被引量:1

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摘要 目的探讨高通量血液透析(HFHD)对中分子毒素及炎症因子的影响。方法 36名维持性血液透析患者,随机分成HFHD组(n=18)和常规血液透析(LFHD)组(n=18),比较治疗前(0个月)、后(3个月)β2微球蛋白(β2-MG)、C反应蛋白(CRP)水平。结果治疗前,两组间血清差异无统计学意义(P>0.05);与治疗前比较,治疗3月后HFHD组血清β2-MG和CRP浓度均显著降低(P<0.05),而LFHD组血清β2-MG和CRP差异无统计学意义(P>0.05)。结论 HFHD能有效清除β2-MG,改善患者慢性炎症状态,提高患者生活质量。
出处 《中国实用医药》 2012年第5期118-119,共2页 China Practical Medicine
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