脑恶性肿瘤超选择动脉化疗并发症的发生与预防(附12例报告)

Transarterial Chemotherarp(12 cases report)

报告１２例脑肿瘤超选择动脉化疗并发症患者，其中２例出现眼部刺激症状，６例出现神经功能障碍（１例引发脑梗塞），１２例患者均出现头疼、恶心与呕吐。脑动脉选择插管由于微导管口位于眼动脉开口以上，故眼部刺激症状较颈内动脉灌注显著减少，微导管应用又易使导管插入脑动脉末梢支，反复插管引起机械刺激，从而使血管痉挛、闭塞而引发神经功能障碍，使其成为超选择动脉内插管最严重的并发症。并同时探讨了并发症的预防措施。

To analyze the complications caused by superselective transarterial chemotherarp 12 cases of mlignant brain tumor2 casas presented signs of ophthalmic stimulation6 cases presented signs of neurological dysfunction(1 case presented cerebral infarction)All 12 cases presented headache,nausea and vomitting Selective catheterization of cerebral arteries caused less and milder ophthalmic stimulation than internal carotid arterial infusion since the outlet of microcatheter lied aboved the entrance of ophthalmic arteryThe application of microcatheter could reach the distal portion of cerebral artery and more easily cause mechanical stimulation,which resulted in neurological dysfunction by means of vasospasm and occlusionThis composed of the most serious complication of superselective transarterial catheterizationPreventive measures of complications were discussed