吉兰-巴雷综合征患者神经电生理检测分析

Electroneurophysiological detection in patients with Gullain barre syndrome

目的:探讨吉兰-巴雷综合征(GBS)的电生理改变特点。方法:对45例GBS患者进行运动神经传导速度(MCV)、感觉神经传导速度(SCV)、肌电图和F波进行检测。共检测160条运动神经、100条感觉神经、及150块肌肉。结果:MCV减慢为60.6%,SCV减慢为49.0%,EMG提示神经源性改变占66.6%,F波异常占88.42%。结论:GBS为广泛周围神经损害,存在以脱髓鞘为主伴有轴索变性的电生理改变。神经电生理检测对GBS的诊断是极为重要的诊断手段。

Objective：To explore the electroneurophysiological characteristics in patients with Gullain barre syndrome.Methods：MCV,SCV,EMG and F wave were measured in 45 patients with GBS clinically diagnosed.A Total of 160 motor nerves,100 sensory nerves and 150 muscle masses were detected.Results：In nerves examination showed that slow MCV and SCV were 60.6% and 49.0%,EMG revealed neurogenic changes in 66.6%,F wave abnormality was noted in 88.42%.Conclusion：GBS might result in widespread peripheral nerve damage.The dominated electroneuophysiological changes might show peripheral nerve demyelination accompanied by axone degeneration.The electroneuphysiological detection might be a very important method for the diagnosis of GBS.