舒利迭辅助治疗对慢性阻塞性肺疾病肺功能的影响

Influence of Seretide auxiliary treatment on lung function of chronic obstructive lung disease

目的探讨舒利迭辅助治疗COPD患者肺功能的影响。方法将我院收治的60例COPD患者随机分为观察组和对照组,每组30例,两组都均采用基础治疗,对照组加用孟鲁司特,观察组在对照组的基础上采用舒利迭辅助治疗,比较两组患者的临床疗效、肺功能、治疗前后的血气指标变化。结果观察组的总有效率为90.0%显著高于对照组的76.7%,P<0.05。观察组治疗后的1 s用力呼气量(FEV1)、用力呼气流量(PEFR)及肺活量最大呼气流速(FRF)、动脉二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)显著优于对照组,P<0.05。结论舒利迭辅助治疗COPD的疗效较好,能够显著改善患者的肺功能和血气指标。

Objective To explore the influence of Seretide auxiliary treatment on lung function of chronic obstructive lung disease.Methods From Dec.2009 to Jun.2010,60 patients with COPD were randomly divided into trial group and control group,30 cases in each group.Both groups all received foundation treatment,the control group plus Montelukast,and the observation group plus based on the control group.Clinical curative effect,pulmonary function and blood gas index were compared between two groups before and after treatment.Results The total effective rate of the observation group（90.0%） significant higher than those in the control group（76.7%）,with significant difference（P0.05）.1 s forced expiratory volume（FEV1）,forced expiratory flows（PEFR） and vital capacity biggest expiratory flow（FRF）,artery carbon dioxide points pressure（PaCO2）,blood oxygen partial pressure（PaO2） in the observation group after treatment improved more significantly than those in control group,with significant differences（P0.05）.Conclusion Seretide auxiliary treatment on chronic obstructive pulmonary disease had better curative effect,and can significantly improve pulmonary function and blood gas index in patients.