妊娠合并宫颈上皮内瘤变80例分析

Analysis of 80 patients with cervical intraepithelial neoplasia during pregnancy

目的：观察妊娠期宫颈上皮内瘤变（C IN）的发展与转归,并探讨妊娠对C IN的影响。方法：80例妊娠妇女人乳头瘤病毒（HPV）检测阳性,确诊C IN后,每8周进行1次阴道镜下取材宫颈液基细胞（TCT）检测至产后6~8周。结果：80例中有78例（97.5%）逆转,1例不变,1例有进展。结论：妊娠对C IN影响不大,可根据患者生育要求,继续妊娠并进行监测随访到产后6~8周,再进行相应治疗或随诊。

Objective：To observe the development and recovery of patients with cervical intraepithelial neoplasia（CIN） during pregnancy,to investigate the influence of pregnancy on CIN.Methods：The result of eighty patients were positive by human papillomavirus（HPV） testing,all patients was CIN.Thinprep cytologic test under col poscopy was done every 8 weeks till 6～8 weeks postnatal.Results：The positive deteriorate rates were 97.5%（78/80）,one case remains and one develops.Conclusion：Pregnancy has little influence on CIN.The pregnancy is allowed to go on according to the patients′ requests.Besides,The doctors should monitor and follow-up till 6～8 weeks after pregnancy and make corresponding treatment and follow-up.