肺癌手术患者用血情况及输血相关因素分析

Analysis of clinical blood transfusion and transfusion-related factors for patients with lung cancer during perioperative period

目的了解该院肺癌切除术患者围术期用血情况及输血相关因素。方法对108例开胸探查肺癌切除术患者临床资料及输血情况进行分析,并对输血相关因素进行单因素和多因素logistic回归分析。结果 108例患者中有22例至少输注了1U红细胞,输血率为20.37%;术前贫血、术前血红蛋白浓度、手术持续时间、身体质量指数(BMI)、术中失血量是患者是否需输血的影响因素(P<0.05);性别、年龄、手术部位、组织学分类、T/N分期和血型对围术期是否需输血无显著性影响(P>0.05)。结论术中失血量、BMI、术前贫血与否是患者是否需输血的主要决定因素,手术持续时间和术前血红蛋白浓度也是需要考虑的因素。

Objective To understand the application of clinical blood transfusion and transfusion-related factors in patients with lung cancer during perioperative period.Methods Clinical data and information of blood transfusion of 108 cases of patients accepting thoracotomy lung resection were analyzed,and blood transfusion-related factors were also analyzed by univariate and multivariate logistic regression analysis.Results Among 108 cases of patients,22 cases,accounting for 20.27%,received at least 1 U of red blood cells during perioperative period.Preoperative anemia,preoperative hemoglobin level,operative duration,body mass index（BMI） and intraoperative blood loss were effective factors for conditioning perioperative blood transfusion practice（P0.05）.Age,sex,histology classification,operative site,T/N stages and blood type did not affect perioperative blood transfusion practices.Conclusion Intraoperative blood loss,BMI and preoperative anemia might be determinative factors for blood transfusion,and operative duration and preoperative hemoglobin level should also be considered.