疑似肺癌患者经纤支镜取材抗酸杆菌检查结果分析

Analysis of acid-fast bacilli examination in suspected patient with lung cancer by fibre bronchoscope

目的探讨疑似肺癌患者经纤支镜取材抗酸杆菌检查的结果。方法对2008～2010年3389例经纤支镜不同方式取材抗酸杆菌检查的结果进行回顾性分析。结果抗酸杆菌总阳性率为6.3%(215/3389);阳性标本中,刷片占56.7%(122/215),灌洗液占88.4%(190/215),两者比较差异有统计学意义(P<0.05)。结论经纤支镜灌洗液取材可提高对抗酸杆菌的检出率,有助于肺癌和肺结核的鉴别诊断。联合采用纤支镜刷片和灌洗液取材,可进一步提高抗酸杆菌检出率。

Objective To investigate the result of acid-fast bacilli examination in suspected patients with lung cancer by fibre bronchoscope.Methods Results of acid-fast bacilli examination by fibre bronchoscope in 3 389 suspected patients with lung cancer during 2008 and 2010 were retrospectively analyzed.Results The total positive rate of acid-fast bacilli was 6.3%（215/3 389）.In positive specimens,56.7%（122/215） were brush smear and 88.4%（190/215） were lavage fluid,between which there was significant difference（P0.05）.Conclusion Lavage fluid collected by fibre bronchoscope could enhance the detection rate of acid-fast bacilli,being helpful for the differential diagnosis of lung cancer and pulmonary tuberculosis.Combined usage of brush smear and lavage fluid could further enhance the detection rate.