电针与帕罗西汀治疗脑卒中后抑郁症33例临床观察

Clinical Observation of Combined Acupuncture and Paroxetine in Treating 33 Cases of Post-stroke Depression

目的观察电针与药物结合治疗脑卒中后抑郁症(PSD)的临床疗效。方法将33例PSD患者随机分为治疗组(17例)和对照组(16例),治疗组采用电针加帕罗西汀治疗,对照组单纯采用帕罗西治疗,治疗6周后观察两组的临床疗效。结果治疗组总有效率为88.2%,对照组为62.5%,治疗组疗效优于对照组(P<0.01);两组治疗后汉密顿抑郁量表(HAMD)评分均较治疗前显著降低(P<0.01),且治疗组HAMD评分明显低于对照组(P<0.01)。结论电针与药物结合治疗PSD的疗效显著,值得临床推广使用。

Objective To observe the clinical efficacy of acupuncture and medicine in the treatment of post-stroke depression（PSD）.Methods 33 cases were randomized into treatment group in which 17 cases were treated with acupuncture and paroxetine,and control group in which 16 cases were treated with paroxetine alone,with a course of 6 weeks.Results The total effective rate was 88.2% in the treatment group and 62.5% in the control group,with a statistically significant difference between them（P0.01）;after treatment,the hamilton depression scale（HAMD）scores were obviously reduced in both groups（P0.01）,with a more significant reduction in the treatment group HAMD than in the control group（P0.01）.Conclusion Combined acupuncture and medicine has excellent results in the treatment of PSD,which is worth of clinical use.