经鼻持续气道正压通气治疗新生儿呼吸衰竭的效果及评价

Effect and Evaluation of Nasal Continuous Positive Airway Pressure on Treatment of Newborns with Respiratory Failure

目的探讨经鼻持续气道正压通气(NCPAP)治疗新生儿呼吸衰竭及其疗效。方法新生儿呼吸衰竭患儿38例,在综合治疗基础上给予NCPAP,观察NCPAP应用后,患儿呼吸频率、心率、血压、动脉血氧分压(PaO2)、氧合指数(PaO2/FiO2)、二氧化碳分压(PaCO2)的变化。结果 NCPAP应用后,患儿呼吸频率、心率、血压、PaO2、PaO2/FiO2、PaCO2有明显改善(P<0.01)。结论 NCPAP可明显改善患儿呼吸功能,减少气管插管机械通气的使用,减少患儿痛苦。

Objective To explore the clinical effect of nasal continuous positive airway pressure（NCPAP） on the treatment of newborns with respiratory failure.Method 38 cases of newborns with respiratory failure was given by NCPAP on the basis of the comprehensive treatment.The respiratory rate,heart rate,blood pressure,partial pressure of oxygen in arterial blood（PaO2）,ratio of partial pressure of arterial O2 to the fraction of inspired O2（PaO2/FiO2） and partial pressure of carbon dioxide in the arterial blood（PaCO2） were observed after the application of NCPAP.Results After the application of NCPAP,the respiratory rate,heart rate,blood pressure,PaO2,PaO2/FiO2 and PaCO2 improved significantly.Conclusions NCPAP can not only improve respiratory function in children,but also reduce the use of mechanical ventilation by endotracheal intubation and relieve the pain.