应用TOPSIS-RSR评价幽门螺杆菌6种检测方法诊断效能

Use of TOPSIS-RSR to evaluate the diagnostic efficiency of 6 detection methods of Helicobacter pylori

目的综合评价幽门螺杆菌(Hp)感染常用6种检测方法的诊断效能,为寻找最优检测方法提供参考。方法通过文献回顾确定Hp 6种检测方法诊断效能的影响因素并建立指标体系,用TOPSIS-秩和比法(RSR)对各方法进行排序和分档。结果排序分档结果为优:幽门螺杆菌粪便抗原检测(HpSA)(Ci=0.827);良:病理组织学(Ci=0.733),快速尿素酶(Ci=0.666),血清学(Ci=0.613);中:13 C-尿素呼气试验(13 C-UBT,Ci=0.560),细菌培养(Ci=0.494)。结论评价结果全面反映了6种检测方法的实际情况,TOPSIS-RSR法是一种可以在Hp检验法评估中灵活应用的方法。

Objective To evaluate the diagnostic efficiency 6 commonly used detection methods of Helicobacter pylori（Hp） infection,and to provide reference for searching the most effective method.Methods On the basis of literature review,influencing factors of the diagnostic efficiency of the 6 commonly used detection methods of Hp were examined,and an evaluation index system was established,in which TOPSIS-RSR was then used to rank and classify the 6 detection methods.Results The results of ranking and classification were：extremely good：HpSA（Ci=0.827）;strongly good：Histopathology（Ci=0.733）,Rapid Urease（Ci=0.666）,and Serology（Ci=0.613）;moderately good：13C-UBT（Ci=0.560） and culture（Ci=0.494）.Conclusion The analytic result has comprehensively reflected the actual diagnostic efficiency of each detection method.TOPSIS-RSR is a reasonable and flexible method that can be used in the evaluation of Hp testing methods.