CT检查脾肝体积比与肝硬化病理改变相关关系

Relationship between pathological change in hepatocirrhosis and spleen-liver volume ratio examined by CT

目的探讨脾肝体积比与肝硬化病理改变间的关系。方法通过手术方式获取所选患者标本,计算病理切片中的假小叶数目∶正常肝小叶数目,根据CT片计算脾肝体积比,统计假小叶数目∶正常肝小叶数目和脾肝体积比及患者术后肝功能评分的关系。结果假小叶数目∶正常肝小叶数目和患者术后肝功能评分直接相关,随着假小叶数目∶正常肝小叶数目的升高,患者术后改良肝功能评分明显升高(t=5.689,P<0.001),同样假小叶数目∶正常肝小叶数目与脾肝体积比也密切相关(t=2.934,P<0.001)。结论假小叶数目∶正常肝小叶数目可以考虑作为肝硬化的病理指标,脾肝体积比和肝硬化的病理改变程度密切相关。

Objective To investigate the relationship between pathological change in hepatocirrhosis and spleen-liver volume ratio.Methods All the cases were received from operations.The ratio of pseudolobule number to hepatic lobule number was calculated.Spleen-liver volume ratio was calculated by CT.Relationship among pseudolobule-hepatic lobule number ratio,spleen-liver volume ratio,and liver function was evaluated.Results Positive correlation was found between the pseudolobule-hepati lobule number ratio and p liver function（t=5.689,P0.001）,also pseudolobule-hepati lobule number ratio and spleen-liver volume ratio were closely related（t=2.934,P0.001）.Conclusion Pseudolobule-hepati lobule number ratio could be regarded as a pathological index in assessment of hepatocirrhosis degree,and spleen-liver volume ratio showed an indirect correlation with hepatocirrhosis degree.