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潜在转化生长因子β结合蛋白2在子宫内膜癌中的表达及其临床意义 被引量:5

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摘要 目的通过检测子宫内膜癌组织中潜在转化生长因子β结合蛋白2(LTBP2)的表达,探讨其对子宫内膜癌发病及预后的指导意义。方法采用免疫组化SP法对97例子宫内膜癌瘤组织和30例正常对照的增生期子宫内膜组织进行LTBP2表达情况的检测。结果正常对照组LTBP2阳性率为15%,子宫内膜癌组为91.8%,两组比较P<0.05。子宫内膜癌组织中LTBP2阳性表达率与组织细胞分化级别、临床分期及不良预后等因素有关。结论子宫内膜癌组织中LTBP2呈阳性表达,LTBP2在子宫内膜癌的发生发展过程中发挥重要作用。
出处 《山东医药》 CAS 2012年第12期81-83,I0004,共4页 Shandong Medical Journal
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