8HotchKiss RS , Karl IE. The pathophysiology and treatment of sepsis[J]. N Engl J Med,2003,348(2): 138-150.
9Bone RC,Balk RA,Cerra FB,et al, Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis, chest, 1992,101(6): 1644-1655.
10Angus DC,Linde-Zwirble WT, Lidicker J,et al. Epidemiology of severe sepsis in the United States: analysis of ineidened, outcome,and associated costs of care[J]. Crit Care Med, 2001,29 (7): 1303-1310.