摘要
针对不同COMT基因型的被试者,首次利用视觉事件相关电位P3来观测被试者在长时间心算任务中COMT基因多态型与脑皮层电生理的关系。选取20名不同基因型人员作为被试者,在执行9组不同难度的心算任务后即刻,进行5 min的3-back任务,探讨健康成人数字工作记忆能力变化情况。Val/Val基因型的被试者P3波幅显著高于Val/Met基因型(P<0.01),但和Met/Met基因型被试者的波幅无差异;Val/Met基因型被试者在不同的工作记忆任务中都显示了最差的成绩。
It was the first to use P3 visual event-related potentials to explore the relationships between COMT polymorphism and cortical physiology in mental arithmetic tasks for a long time.20 different genotype subjects were chosen for 9-group mental arithmetic work of different workload,followed immedi-ately by 5 minutes＇ 3-back task so as to observe the changes of numerical working memory ability of healthy adults.P3 amplitude of the subjects with Val/Val homozygote is significantly higher than the subjects with Val/Met homozygote（P0.01）.But compared to the subjects with Met/Met homozygote,there is no distinct significance in P3 amplitude.Val/Met heterozygous individuals show poorer performance compared to those with other genotypes.
出处
《体育科研》
2012年第2期75-78,100,共5页
Sport Science Research
