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基于谱域光学相干反射测量术的生物组织折射率测量技术 被引量:1

Measurement of the Refractive Index of Bio-Tissues Based on Spectral Domain Optical Coherence Reflectometry
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摘要 提出了基于谱域光学相干反射法的生物组织折射率测量技术,设计了共光路干涉结构,提高了测量速度,抗干扰能力强。中心波长为850nm的宽带光源发射的光经Y型耦合器传输到样品端,由样品散(反)射后,回射入样品臂,经Y型耦合器传输到光谱分析系统,使用计算机虚拟仪器完成系统构建与优化。编写快速傅里叶变换程序进行信号分析。使用标准K9玻璃样片作为样品进行验证,实验误差为0.29%。实际测量了黄瓜浅表切片在850nm波长处的折射率,测量时间小于1min。 We present a method for measuring the refractive index of bio-tissues based on spectral domain optical coherence reflectometry(SD-OCR).Common-path method is used to simplify the system structure and improve the measuring speed.It has a strong anti-interference ability.Broadband light(central wavelength 850 nm) is transmitted through the Y-coupler and scattered(reflected) back to the spectrum analyzing system by the specimen through the sample arm and the Y-coupler.The system construction and optimization are then realized by virtual instruments.Fast Fourier transformation(FFT) is employed to analyze signals.This theory is verified by a standard K9 glass sample and the results show that the experimental error is 0.29%.The refractive index of a cucumber superficial slice at 850 nm is measured and the measuring time is less than 1 min.
作者 刘智 朱永凯
出处 《激光与光电子学进展》 CSCD 北大核心 2012年第4期75-80,共6页 Laser & Optoelectronics Progress
基金 南京航空航天大学基本科研业务费专项科研项目(NS2011017)资助课题
关键词 光学测量 生物组织 折射率 谱域光学相干反射测量术 傅里叶变换 optical measurement biological tissues refractive index spectral domain optical coherence reflectometry(SD-OCR) Fourier transformation
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参考文献12

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