速度向量成像技术对原发性高血压病合并2型糖尿病患者颈动脉弹性的初步评价

Preliminary assessment of carotid arterial elasticity in patients with hypertension combined with type 2 diabetes by velocity vector imaging technique

目的应用速度向量成像(VVI)技术初步评价原发性高血压病合并2型糖尿病患者颈动脉的运动特点。方法选取我院原发性高血压病患者22例(高血压病组),原发性高血压病合并2型糖尿病患者26例(合并糖尿病组),另选同期健康体检者25例作为对照组;应用VVI技术检测三组颈总动脉的正向峰值应变(S+max)、负向峰值应变(S-max),正向峰值应变率(SR+max)及负向峰值应变率(SR-max)。结果合并糖尿病组颈动脉S-max和S+max均显著小于对照组(P<0.05);高血压病组颈动脉S-max和S+max与对照组比较差异无统计学意义(P>0.05);三组组内颈动脉各壁间S-max和S+max比较,差异均无统计学意义(P>0.05)。合并糖尿病组、高血压病组颈动脉SR-max均显著小于对照组(P<0.05),合并糖尿病组颈动脉SR-max显著小于高血压病组和对照组,差异有统计学意义(P<0.05);高血压病组颈动脉SR+max显著小于对照组差异有统计学意义(P<0.05);三组组内颈动脉各壁间SR-max和SR+max比较,差异均无统计学意义(P>0.05)。结论 VVI技术可较好地判断原发性高血压病合并2型糖尿病患者颈总动脉管壁弹性改变情况,为临床早期诊断动脉硬化提供依据。

Objective To study the motion features of carotid artery in patients with hypertension combined with type 2 diabetes （ DM 2） by velocity vector imaging （VVI） technique. Methods Twenty-two patients with hypertension （ hypertension group）, 26 patients with hypertension combined with DM 2 （DM 2 combined with hypertension group） ,and 25 healthy subjects as control group were enrolled in this study. Their nagative maximum strain （ S-max ） , positive maximum strain （ S ＋max ） , nagative maximum strain rate（SR-max） and positive maximum strain rate （SR＋max） of common carotid artery were measured by VVI. Results The S-max and S＋max in DM 2 combined with hypertension group were lower than those in control group （P〈 0. 05 ）, there was no significant difference of S-max and S＋max between hypertension group and control group（ P〉0.05 ）. There was no significant difference of S-max and S＋max, among three groups （P〉0.05）. The SR-max in the DM 2 combined with hypertension group and hypertension group was lower than those in control group （ P 〈 0.05 ）. The SR ＋max in the DM 2 combined with hypertension group was utmostly lower than those in control group（P〈0.01 ）. The SR-max in hypertension group were lower than that in control group（P〈0.05 ）. There was no significant difference of SR-max and SR＋max among three groups （P〉0.05）. Conclusion VVI technique can evaluate the changes of common carotid arterial wall in patients with hypertension combined with DM 2, it can provide reliable information for clinical early diagnosis.