实验猕猴全身CT影像学观察

Observation of whole body CT tomography of the laboratorial rhesus monkey

目的:应用CT技术对成年实验猕猴全身进行断层扫描,探讨CT技术对猕猴疾病的临床诊断意义,建立正常成年猴CT影像图谱,为CT技术在猕猴解剖学的研究、疾病的诊断及科学实验方面的应用,提供影像学的基础资料。方法:(1)选择实验猕猴10只,雌雄各半,年龄6～10岁,进行全身CT断层扫描。(2)试验猴全身麻醉后,置于CT诊断床上,取头前尾后仰卧位,采用平扫及增强扫描技术,进行容积数据采集,获取正常猕猴全身CT影像图片。(3)利用CT图像后处理技术对扫描获得的容积数据进行2D或3D图像重组处理。结果:(1)获得实验猕猴活体结构CT连续断层图像数据集。(2)从扫描和重建图像中精选具有解剖意义的图像,编辑建立实验猕猴CT影像图谱。文中展示4幅代表性扫描图片和5幅三维重建图像。(3)从比较解剖学的角度,阐述猕猴结构特点及与人类的区别。结论:(1)CT影像能够较好显示及分辨猕猴的组织器官结构,骨骼、大血管界面清晰;但软组织、神经、肌肉组织等显示不够清晰。(2)试验获得了正常成年猕猴全身的影像学基础资料,为CT技术在猕猴影像学研究、解剖学研究、疾病的临床诊断及科学实验方面的应用,提供了参考。(3)在猕猴CT影像学方面做了初步摸索,对猕猴进行CT扫描的技术参数选择及猕猴各器官组织定量统计数据的建立等有待进一步总结和完善。

Purpose To research the clinical diagnosis of disease in rhesus monkey with the observation of whole CT tomography of the healthy adult laboratorial monkey, to establish the maps of CT tomography of the healthy adult rhesus monkey, to provide ？the basic image？data of CT technology in the applications of anatomy, clinical diagnosis and scientific experiments of rhesus monkey. Methods （1） 10 laboratorial monkeys were selected for whole body CT tomography. （2）After general anesthesia, the monkeys were placed in supine position and the volume data were collected to obtain the whole body CT images of normal rhesus monkey by using plain and enhanced scanning technology. （3）The scan obtained volume data were restructured into 2D or 3D images using CT image post- processing technology. Results （1）the Continuous CT tomography data set of living rhesus monkey were obtained. （2）From the CT tomography images, anatomical images were carefully selected and edited to establish the CT tomography map of ？laboratorial rhesus monkeys. There are 4 representative CT tomography images and 5 3D restructured images in this paper. （3）Describes the rhesus monkey＇s physiological structural characteristics and the difference between rhesus monkey and human. Conclusion （1）CT tomography image can clearly display and distinguish the rhesus monkey＇s structure of tissues and organs. （2）The fundamental imaging data obtained in the test provide a reference of CT tomography technology in the field of rhesus monkey anatomy research, clinical diagnosis of disease and scientific experiments. （3）Some preliminary results of rhesus monkey CT tomography imaging were seen in this paper, further study will be done in the field of selection of parameters of rhesus monkey CT tomography technology and establishing of quantitative statistics data of rhesus monkey organs and tissues.