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血清高尔基体蛋白73检测在肝病患者中的意义 被引量:2

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摘要 高尔基体蛋白73(GP73)是存在于高尔基体的一种跨膜蛋白,Kladney等于2000年首先描述了其在正常人体中的表达,GP73主要由胆管上皮细胞表达,后续研究提出病毒感染(HBV和HCV)及非病毒原因(酒精性肝病及自身免疫性肝病)引起的肝病患者中,GP73水平显著上调^[1][2],随后研究又提出GP73可作为肝癌的的一个可靠标志物,并且国内也有较多用于肝细胞癌诊断的报道^[3-4]。本文通过对肝病患者及对照组血清GP73等指标的检测,意在探讨GP73在肝病患者中的应用价值。
出处 《放射免疫学杂志》 CAS 2012年第2期219-220,共2页 Journal of Radioimmanology
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