大面积撕脱伤术后创面真菌感染的临床研究

Clinical study of fungal infections after large-scale avulsion wound

目的探讨大面积撕脱伤术后创面真菌感染的构成及临床诊治措施。方法对手外科大面积撕脱伤术后切口真菌感染患者进行回顾性分析。结果 280例手外科患者共分离出真菌36株,其中白色假丝酵母菌占58.3%,是最主要的致病菌株;患者基础疾病和术后长期、多种广谱抗菌药物联合使用是真菌感染的重要因素。结论真菌感染是大面积撕脱伤术后的重要并发症,白色假丝酵母菌是主要病原菌,对术后患者真菌感染应采取积极预防、及时发现和有效治疗。

OBJECTIVE To investigate the distribution of fungal infections after large-scale avulsion wound surgery and explore the measures for clinical treatment. METHODS Patients with fungal infections after large-scale avulsion wound surgery were retrospectively analyzed. RESULTS Totally 36 strains of fungi were isolated from 280 patients, among which Candida albicans were the predominant pathogens, accounting for 58. 3% the primary diseases and long-term use of multiple broad spectrum antibiotics after operation were risk factors for fungal infections. CONCLUSION Fungal infection is the main complication after large-scale avulsion wound surgery, C. albicans is the predominant pathogens it is necessary to take active measures for prevention and treatment of fungat infections in patients.