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膜联蛋白A2异常表达与消化道肿瘤发生、发展的关系 被引量:4

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摘要 膜联蛋白(annexin,ANX)是一类受Ca2+调节、能够结合带负电荷膜磷脂的蛋白超家族,家族有12个成员(A1~A11,A13),它们的基因定位及相互作用蛋白见表1[1],蛋白分子包含数个长重复序列的同源性区域,每个长重复序列由70个氨基酸组成,含有凸面和凹面。凸面面向胞膜,包含钙离子和磷脂结合位点,凹面包含氨基末端和羧基末端,广泛存在于细胞质膜下、
出处 《中华临床医师杂志(电子版)》 CAS 2012年第4期103-106,共4页 Chinese Journal of Clinicians(Electronic Edition)
基金 江苏省医学重点项目(K200102) 江苏省高校优势学科建设基金(PAPD)
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