曲伏前列素治疗超声乳化联合房角分离术后的闭角型青光眼

Effect of travoprost on patients with angle-closure glaucoma after the surgery of phacoemulsification and goniosynechialysis

目的:观察曲伏前列素滴眼液治疗超声乳化联合房角分离术后的闭角型青光眼患者的降眼压效果。方法:超声乳化联合房角分离术后眼压控制不理想的闭角型青光眼11例(11眼),术后4周测量眼压后予每晚1次0.004%曲伏前列素滴眼液滴眼,分别于用药后1、2、4周测量9时及16时眼压、视野及房角。比较用药前后的眼压值。结果:与曲伏前列素滴眼液治疗前相比,用药后1、2、4周眼压下降明显(P<0.01)。结论:曲伏前列素滴眼液治疗超声乳化联合房角分离术后高眼压的闭角型青光眼是安全、有效的。

Objective：To investigate the efficiency of travoprost in lowering patients′ intraocular pressure who contained angle-closure glaucoma even after phacoemulsification and goniosynechialysis.Methods：Eleven angle-closure glaucoma patients whose intraocular pressures were not ideal after phacoemulsification and goniosynechialysis were selected.Four weeks after surgery,the intraocular pressure was measured,and the eyes were treated with 0.004% travoprost once every night.Intraocular pressure at 9am and 16pm,visual acuity,and visual field were checked at the first,second,forth week after travoprost treatment.Finally,the intraocular pressure values after treatment were compared with before treatment.Results：In contrast to before treatment of travoprost,at the first,second,forth weeks after treatment,the average intraocular pressure was reduced obviously（P〈0.01）.Conclusions：Travoprost was safe and effective in treatment of angle-closure glaucoma after phacoemulsification and goniosynechialysis.