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肿瘤标志物在卵巢癌早期诊断的研究进展

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摘要 肿瘤标志物(tumormarker,TM)是指存在于肿瘤细胞内或肿瘤细胞表达及脱落的物质,或是宿主对体内肿瘤反应而产生的物质。其存在于细胞胞质、胞核中或细胞膜表面,也可见于循环血液、其他体液或组织中。这些物质,有的只见于胚胎中;有的只在肿瘤患者体内出现;还有的在肿瘤患者体内超过正常人含量。卵巢癌的早期诊断,目前主要集中于免疫学、影像学和基因组学等方面,而免疫学TM研究尤其备受关注。
出处 《蚌埠医学院学报》 CAS 2012年第3期367-369,共3页 Journal of Bengbu Medical College
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  • 1杨永彬,徐伟,陈建利,万小平.卵巢癌肿瘤标志物研究进展[J].国外医学(妇产科学分册),2004,31(4):229-232. 被引量:24
  • 2胡成进,沈茜,陈英剑,闻新棉.乳腺癌klk6基因表达的实时荧光定量法的建立及初步应用[J].中华检验医学杂志,2005,28(6):610-612. 被引量:10
  • 3Gadducci A, Cosio S, Carpi A, et al. Serum tumor markers in the management of ovarian, endometrial and cervical cancer. Biomed Pharmacother,2004,58 : 24 -38.
  • 4Meyer T, Rustin GJ. Role of tumour markers in monitoring epithelial ovarian cancer. Br J Cancer,2000,82 : 1535-1538.
  • 5Hellstrom I, Raycraft J, Hayden-Ledbetter M, et al. The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. Cancer Res, 2003,63 : 3695 -3700.
  • 6Israeli O, Goldring-Aviram A, Rienstein S, et al. In sihco chromosomal clustering of genes displaying altered expression patterns in ovarian cancer. Cancer Genet Cytogenet,2005 ,160 :35- 42.
  • 7Drapkin R, von Horsten HH, Lin Y, et al. Human epididymis protein 4 ( HE4 ) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res, 2005, 65:2162-2169.
  • 8Kirchhoff C, Habben I, Ivell R, et al. A major human epididymisspecific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors. Biol Reprod, 1991,45: 350- 357.
  • 9Moore RG, Brown AK, Miller MC, et al. The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass. Gynecol Oncol,2008,108:402-408.
  • 10SinghJ, Naran A, Misso NL, et al. Expression of kalfikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma[J]. Int Immunopharmacol. 2008,8(2) :300-306.

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