克拉玛依市区35岁以上鼾症人群高血压患病率调查

Epidemiologic study the prevalence of hypertension in snoring in adults aged over 35 years in Kelamayi city

目的调查克拉玛依市区鼾症患者中高血压的患病率，探讨鼾症、夜间低氧与高血压的关系。方法采用流行病调查的方法对克拉玛依市区3个社区1144例35岁以上常住居民进行人户睡眠鼾症问卷及高血压病史调查。问卷内容包括打鼾情况、测量身高、体质量、血压、颈围、腹围、腰围及臀围。并对鼾症及非鼾症人群进行夜间血氧监测。结果鼾症组（629例）与非鼾症组（515例）间在体质量指数（BMI）[（26．7±3．9）kg／m2比（25．6±4．1）kg／m2]、颈围[（36．5±3．4）cm比（35．6±3．1）cm]、腹围[（92．8±11．3）cm比（89．8±11．3）cm]、氧减指数（ODI4）[（11．0±11．0）次／h比（6．5±7．4）次／h]、夜间平均氧饱和度（MSaO2）[（92．8±4．5）％比（93．3士2．8）％]、夜间最低氧饱和度（LSaO2）[（82．6±6．3）％比（84．0±8．0）％]、收缩压[（130．3±18．3）mmHg比（125．1±16．5）mmHg]和舒张压[（82．8土12．7）mmHg比（78．5±12．1）mmHg]等方面差异有统计学意义（P值均〈0．01）。夜间低氧组与无低氧组间在BMI[（26．7±4．1）kg／m2比（25．5±3．7）kg／m2]、颈围[（36．4±3．4）cm比（35．6±3．1）cm]、腹围[（93．4±11．3）cm比（88．4±10．8）cm]、收缩压[（130．2±17．8）mmHg比（124．5±17．o）mmHgJ和舒张压[（82．2±12．6）mmHg比（78．7±12．3）mmHg3等方面差异有统计学意义（P值均〈0．01）。鼾症组与非鼾症组间高血压患病率（32．9％比20．2％）差异有统计学意义（P值均〈0．01）。夜间低氧组与无低氧组间高血压患病率（35．9％比17．1％）差异有统计学意义（P值均〈0．01）。结论克拉玛依市区鼾症人群中高血压的患病率为32．9％，高血压与鼾症及夜间低氧相关，打鼾和夜间低氧可引起血压增高，应引起重视。

Objective To study the prevalence of hypertension in snoring in adults aged over 35 years in Kelamayi city,and relationship among snoring, nocturnal desaturation and hypertension. Methods 1 144 subjects （age≥35） were derived from the population living in three districts in Kelamayi city. All subjects were asked at home to answer questions about their snoring by himself or bed partner. They were asked to answer the questions concerning snoring, hypertension history etc, and rneaturing the height, weight,neck circumference, abdominal circumference, waistline and hip circumference, and home pulse oximeter testing. Results The body mass index[（26.7±3.9） kg/m2 vs （25.6±4. 1） kg/m2 ], neck circumference [（36.5±3.4） cm vs （35.6±3.1） cm],abdominal circumference [（92.8±1.3） cm vs （89.8±11.3） cm],the number of desaturations≥4% per hour （ODI4） [（11.0±11.0） times/h vs （6.5±7.4） times/hi, the mean nocturnal arterial oxygen saturation （MSaO2）[（92.8±4.5）% vs （93.31±2.8）%],the nadir arterial oxygen saturation （LSaO2） [（82.6 ±6.3） % vs （84.0±8.0） %], systolicBP（SBP） [（130.3 ±18.3） ram Hg vs （125.1±16.5） ram Hg] and diastolic BP （DBP） [（82.8±12.7） mm Hg vs （78.5±12.1） mra Hg] were significantly different hettween with and without snoring groups （ P〈0.01）,The body mass index E（26. 7±4.1） kg/m2 vs （25.5±3.7） kg/m2],neck circumference [-（36.4±3.4） cm vs （35.6±3.1 ） cm], abdominal circumference E（ 93.4±11.3） cm vs （88.4±10.8） cm],SBP[（130.2±17.8） mm Hg vs （124.5±17.0） mm Hg2 and DBP [（82.2±12.6） mm Hg vs （78.7 ±12.3） mm Hg] were significantly different bettween with and without nocturnal desaturation groups （P 〈0.01）, there are significant difference on the prevalence of hypertension between with and without snoring groups （32.9% vs 20.2% ）（ P 〈0.01 ）, there are significant difference on the prevalence of hypertension between with and without nocturnal desaturation （35.9% vs 17.1%） （ P 〈0.01）. Conclusions The prevalence of hypertension of snoring in adults over 35 yr old was 32.9 in Kelamayi city, hypertension correlated with snoring and nocturnal, desaturation, snoring and nocturnal desaturation can to cause hypertension, that the disease needs better understanding and study.