血管内皮生长因子与出血性脑血管病

Vascular endothelial growth factor and hemonhagic cerebrovascular disease

血管内皮生长因子（vascularendothelialgrowthfactor，VEGF）在胚胎发育和多种疾病的血管形成中起着重要作用。近年来，VEGF的神经保护作用日益得到重视。VEGF在出血性脑血管病时表达上调，在脑出血中起着保护作用，但在蛛网膜下腔出血中的作用尚有争议。VEGF与出血性脑血管病的关系密切而复杂，尚需更多研究阐明两者之间的关系，为此类疾病的防治提供新的临床思路。

Vascular endothelial growth factor （VEGF） plays essential roles in embryonic development and angiogenesis of a variety of diseases. In recent years, the neuroprotective effect of VEGF is increasingly receiving attention. The expression of VEGF is upregulated during hemorrhagic cerebrovascular disease. It plays a protective role in cerebral hemorrhage, but its role is controversial in subarachnoid hemorrhage. The relationship between VEGF and hemorrhagic cerebrovascular disease is both close and complex. More research is needed to clarify the relationship between them and to provide new clinical ideas for the prevention and treatment of this kind of disease.