阻塞性睡眠呼吸暂停低通气综合征与高血压病

Obstructive Sleep Apnea Hypoventilation Syndrome and Hypertension

目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与患者高血压的发病情况及其与睡眠对血压的影响。方法:打鼾就诊的374例患者经至少7 h多导睡眠监测及睡前、睡中及醒后血压测定。监测呼吸暂停低通气指数。睡前、醒后血压达到高血压标准情况比较。结果:①睡前血压与睡中、醒后血压有显著性差异(P<0.05),较睡前升高。②除AHI<5外,OSAHS轻、中、重度均有显著性差异(P<0.05)。OS-AHS患者中高血压患病率为69.4%,男性明显高于女性,高血压患病率与呼吸暂停低通气指数的高低成正相关,夜间最低血氧饱和度<80%患者的高血压患病率显著高于其他患者。结论:OSAHS与高血压患病率关系密切,呼吸暂停低通气指数、血氧饱和度等睡眠相关指标与高血压患病率有统计学相关性。

Objective：To investigate the relationship between obstructive sleep apnea hypoventilation syndrome and the incidence of hypertension and the effect of sleep on the blood pressure caused by OSAHS.Methods：Monitoring snoring patient＇s polysomnography（PSG） figure at least seven hours,and measuring bedtime, sleep and wake up blood pressure,monitoring apnea hypoventilation index,and comparing bedtime and wake up blood pressure.SPSS 13.0 software package was used in the data analysis process and prevalence rates of hypertension were analyzed by chi-square test.Results：①Blood pressure was significant difference among sleep,wake up and bedtime（P0.05）.②Except AHI5,mild,moderate and severe OSAHS were significant difference（P0.05）.The incidence of hypertension in all patients with OSAHS was 69.4%,and the male was more than the female.The prevalence of hypertension increased with AHI,and the prevalence of hypertension in patients with the minimum SpO280% was higher significantly than that in other patients.Conclusions：There is a close relationship between OSAHS and the prevalence of hypertension.There were statistical correlation between AHI,SpO2 and hypertension.