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Ki-67表达对胃肠道间质瘤诊断及预后判断的意义

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摘要 目的探讨Ki-67表达对胃肠道间质瘤(GIST)诊断及预后判断的意义。方法采用免疫组化检测61例GIST,并结合病理形态学及生物学行为分级进行分析,观察并比较Ki-67在不同GIST分型中表达情况。结果61例GIST中,Ki-67阳性15例(24.6%)。良性、交界性GIST中Ki-67阳性表达率分别为6.3%、20.0%,低于恶性GIST的53.3%,且良性GIST低于交界性GIST,差异均有统计学意义(P<0.05)。结论 Ki-67的表达与GIST生物学行为关系密切,可作为GIST生物学行为的潜在评价指标,对判断预后具有价值。
作者 张和成
出处 《临床合理用药杂志》 2012年第8期98-98,共1页 Chinese Journal of Clinical Rational Drug Use
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