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Nanog基因及其传导通路在保持胚胎干细胞多能性中的作用 被引量：1

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摘要 胚胎干细胞（embryonicstemcells，ES）的研究最早开始于1980年，当时鼠Es第一次被分离出来，ES来源于囊胚内细胞团（innercellmass，ICM），可以自我复制并分化出其他胚层，这一特性对于细胞替代治疗、药物开发和自我修复治疗等研究具有重要的价值。近些年来人类ES的成功培养和分化受到了很大关注，它可以用于组织冉生治疗和研究人类进化过程。
作者 夏金超 陈凌
机构地区 首都医科大学宣武医院神经外科
出处 《中华临床医师杂志（电子版）》 CAS 2012年第8期144-146,共3页 Chinese Journal of Clinicians(Electronic Edition)
关键词 胚胎干细胞 NANOG基因 传导通路 多能性 细胞替代治疗 人类进化 内细胞团 自我复制
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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二级参考文献53

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共引文献37

同被引文献17

  • 1赖良学,郑瑞珍,秦鹏春,孙方臻.影响体外培养兔胚发育和兔类ES细胞分离的若干因素[J].中国兽医学报,1996,16(1):16-21. 被引量：16
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  • 6Zhao Yun Cheng,Jiapeng Lin,Liqin Wang,et al.Derivation and characterization of ovine embryonic stem-like cell lines in semidefined medium without feeder cells.J Exp Zool,2011,315:639-648.
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引证文献1

中华临床医师杂志（电子版）
2012年 第8期

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