腹腔镜结直肠癌根治性手术的临床疗效分析

Clinical efficacy of laparoscopic radical resection of colorectal cancer

目的:评估腹腔镜手术治疗结直肠癌的临床疗效。方法:回顾性分析2001年3月—2004年5月实施根治性结直肠癌手术146例的临床资料,其中腹腔镜手术72例,传统开腹74例,比较两组术中出血量、手术时间、医疗费用、术后肠道功能恢复时间、术后住院时间、淋巴结清扫数目、术后并发症、近期和远期生存率等情况。结果:两组在术中出血、手术时间、术后肠道功能恢复、术后住院时间等方面差异均有统计学意义(均P<0.05)。而两组间的医疗费用、术后并发症、淋巴结清扫数目及2,5年总生存率无统计学差异(均P>0.05)。结论:腹腔镜手术在术中出血、术后肠道功能恢复时间及术后住院时间方面体现了优势。腹腔镜结直肠癌根治术安全、有效、经济、与传统开腹手术的近、远期临床效果相似。

Objective： To evaluate the clinical efficacy oflaparoscopic surgery for colorectal cancer. Methods： The clinical data of 146 patients undergoing radical resection of colorectal cancer from March 2001 to May 2004 were retrospectively analyzed. The data consisted of 72 cases of laparoscopic surgery and 74 cases of traditional open surgery. The clinical indexes that included operative blood loss, operative time, medical costs, time to postoperative bowel function recovery, postoperative hospital stay, number of lymph nodes dissected, postoperative complications, short- and long-term survival etc. between the two groups were compared. Results： There were significant differences between the two groups with regards to operative blood loss, operating time, postoperative bowel fimction recover）5 and length of postoperative hospital stay （all P〈0.05）. However, the differences had no statistical significance between the two groups in respect of the medical costs, postoperative complications, number of lymph nodes removed, and 2- and S-year overall survival rate （all P〉0.05）. Conclusion： Laparoscopic surgery has advantages in reducing the intraoperative bleeding, time to bowel function recovery and hospital stay. Laparoscopic resection of colorectal cancer is a safe, effective and economic modalit）5 and has similar short- and long-term outcomes as the traditional open surgery.