期刊文献+

消郁安神汤抗肾阴虚型抑郁的初步研究 被引量:2

Preliminary research on anti-depression effects of Xiaoyu Anshen decoction
原文传递
导出
摘要 目的初步探讨自拟消郁安神汤的抗抑郁作用。方法采用小鼠悬尾实验及强迫游泳实验观察消郁安神汤的抗抑郁作用。结果在小鼠强迫游泳实验和小鼠悬尾实验中,消郁安神汤能明显缩短两种"行为绝望"模型小鼠的不动时间,高剂量抗抑郁的效果最明显。结论消郁安神汤对"行为绝望"动物模型有抗抑郁作用。 OBJECTIVE To discuss the anti-depression effects of Xiaoyu Anshen decoction.METHODS Effects of Xiaoyu Anshen decoction was evaluated through mice forced swimming test and mice tail suspension test.RESULTS Xiaoyu Anshen decoction decreased the accumulative immobility time significantly in mice forced swimming test and mice tail suspension test,with high dose decoction being the best.CONCLUSION Xiaoyu Anshen decoction can improve the depressive condition of mice and have obvious effect of antidepression.
作者 秦琴 张浩
出处 《华西药学杂志》 CAS CSCD 北大核心 2012年第2期125-127,共3页 West China Journal of Pharmaceutical Sciences
关键词 抗抑郁 消郁安神汤 悬尾试验 强迫游泳 敞箱实验 Anti-depression Xiaoyu Anshen decoction Tail suspending test Forced swimming test Open-field test
  • 引文网络
  • 相关文献

参考文献4

二级参考文献20

  • 1胡随瑜,彭贵军,宋炜熙,王哲.白松片对抑郁模型大鼠海马脑源性神经营养因子和酪氨酸激酶B表达的影响[J].中国行为医学科学,2005,14(4):292-294. 被引量:18
  • 2夏军,叶慧,周义成,张景峰,夏黎明,王承缘.慢性应激大鼠抑郁模型的建立及其有效性的探讨[J].华中科技大学学报(医学版),2005,34(4):493-495. 被引量:35
  • 3刘贤臣,唐茂芹,胡蕾,王爱祯,吴宏新,赵贵芳,高春霓,李万顺.匹兹堡睡眠质量指数的信度和效度研究[J].中华精神科杂志,1996,29(2):103-107. 被引量:3584
  • 4[1]A BeneLLi,M FiLaferro,A BertoLini,et al.InfLuence of S-adenosy11L1methionine On chronic miLd stress-induced anhedonia in castrated rats[J].British JournaL of PharmacoLogy,1999,127:645-654.
  • 5Porsolt RD. Animal model of depression : Utility for transgenic re- search[ J]. Rev Neurosci, 2000, 11:53.
  • 6Murua VS. Gomrz RA, Andrea ME,et al. Shuttle - box deficits in- duced by chronic variable stress: reversal by imipramine adminis- tration[ J]. Pharmacol Biochem Behav, 1991,38 : 125.
  • 7Herrera DG, Maysinger D, Gadient R, et al. Spreading depression induces c - fos - like immunoreactivity and NGF mRNA in the rat cerebral cortex[ J]. Brain Res, 1993,602:99.
  • 8Luthringer R,Toussaint M,Schahenbrand N,et al.A double-blind,placebo-controlled evaluation of the effects of orally administered venlafaxine on sleep in inpatients with major depression[J].Psychopharmacology Bulletin,1996,32(4):637-646.
  • 9Rechtschaffen A,Kales A.A manual of standardized terminology,techniques,and scoring system for sleep stages in human subjects[M].3rd.Los Angels:Brain Information Service/Brain research Institute of University of Califonia,1973.1-2.
  • 10Berger M,Van Calker D,Riemann D.Sleep and manipulations of the sleep-wake rhythm in depression[J].Acta Psychiatrica Scandinavica.Supplementum,2003,(418):83-91.

共引文献35

同被引文献37

引证文献2

二级引证文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部