Thermodynamic properties of three alkaloids in normal saline

Aim To provide a potent reference for the clinical application of these alkaloids.Method The enthalpy of dissolution for these alkaloids in normal saline are measured using a RD4962000Calvet Microcalorimeter at 36.5℃under atmospheric pressure.Results The differential enthalpy(Δ dif H m) and molar enthalpy(Δ sol H m) were determined for these alkaloids in normal saline.Conclusion On the basis of these experimental data and calculated results,the kinetic equation,half-life,Δ sol H m,Δ sol G m andΔ sol S m of the dissolution process were also obtained.

Aim To provide a potent reference for the clinical application of these alkaloids. Method The enthalpy of dissolution for these alkaloids in normal saline are measured using a RD496-2000 Calvet Microcalorimeter at 36.5℃ under atmospheric pressure. Results py （△difHm） and molar enthalpy （△solHm） were determined for these alkaloid elusion On the basis of these experimental data and calculated results, the ki △sol Hm, △solGm and △solSm of the dissolution process were also obtained The differential enthals in normal saline. Connetic equation, half-life,