两次移植提高反复体外受精-胚胎移植失败患者的妊娠率的研究

Double transfer improve clinical pregnancy rate for patients with repeated IVF-ET failures

在体外受精-胚胎移植（IVF—ET）中，妊娠率通常在40％～50％左右，对于首次进行IVF—ET治疗的患者成功率可达60％，但仍有部分患者在多次1VF—ET后仍然失败，此部分患者再次行IVF的成功率低于总体的成功率，

Objective： To compare IVF outcome following double transfer with that following one transfer among patients with previous multiple IVF failures. Methods： 60 patients with previous more than 2 times IVF failures and with more than 2 available embryos were randomize divided into 2 groups： The study group underwent double transfer of 1 of day 3 embryo and 1-2 of D5 embryos. The control group underwent embryo transfer on day 3 only. Results： Double transfer resulted in a pregnancy rate of 53.3% （16/30）,implantation rate of 19.77% （17/86） compared with 23.3%（7/30） and 7.95%（7/88） following day 3 transfer （P〈0.05）. Conclusion： Double transfer of embryos may be indicated for repeated IVF failure patients with more than 2 available embryos.