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血管内皮生长因子936C/T位点基因多态性与肺癌的相关性

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摘要 目的:探讨血管内皮生长因子(vascular endothelial growth factor,VEGF)936C/T位点基因多态性与肺癌的相关性。方法:以病例对照的研究方法,采用PCR-RFLP技术,对50例肺癌患者和50例对照者的VEGF 936C/T位点基因型进行检测,明确936C/T位点基因型,并行基因多态性与肺癌风险关联性的统计学分析。结果:肺癌患者VEGF 936C/T位点基因型及等位基因分布与对照组比较,差异无统计学意义(P>0.05)。结论:VEGF 936C/T位点基因型及等位基因可能与肺癌的发生、发展无关。
出处 《广西医科大学学报》 CAS 2012年第1期100-101,共2页 Journal of Guangxi Medical University
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