西安地区儿童副流感病毒感染状况分析

Parainfluenza virus infection of children with respiratory tract infections in Xi'an

【目的】分析西安地区儿童副流感病毒(parainfluenza virus,PIV)感染情况及与中性粒细胞减少的关系。【方法】采用酶联免疫吸附(ELISA)法检测血清中副流感病毒特异性IgM抗体(PIV-IgM),血细胞分析仪检测外周血白细胞。【结果】1～6岁年龄组PIV感染阳性率较其他年龄组明显升高,1～3岁年龄组中性粒细胞减少症发生率较高,PIV感染与中性粒细胞减少的发生关系密切。【结论】西安地区儿童呼吸道PIV感染阳性率较高,常规进行病原血清特异性抗体检测有助于临床医生合理用药。

【Objective】 To analyze parainfluenza virus（PIV） infection of children with respiratory tract infections（RTI） and the relationship between neutropenia in Xi＇an. 【Methods】 Specific IgM of PIV with Enzyme-linked immunosorbent assay（ELISA） was detected.Peripheral blood leukocytes were detected by hematology analyzer. 【Results】 PIV infection in 1-6 years age group were significantly higher than other age groups,neutropenia in 1-3 years age group were higher incidence of disease,PIV infection was closely related with neutropenia. 【Conclusions】 PIV infection with respiratory tract infections are higher among children in Xi＇an.It is very useful for clinicians selecting efficient drugs to detect Specific IgM of PIV in routine test in the children of RTI.