平阳霉素加碘化油经肝动脉栓塞治疗肝血管瘤42例临床体会

Clinical Experiences in the Treatment of Hepatic Cavernous Hemangioma by Pingyangmycin and Lipiodol Emulsion Embolization

目的分析经肝动脉插管平阳霉素碘油乳化剂(pingyangmycin lipiodolemulsion,PLE)栓塞治疗肝海绵状血管瘤(CHL)的临床疗效和安全性.方法总结经肝动脉灌注PLE治疗42例肝海绵状血管瘤的临床资料,并随访6～18个月观察疗效及并发症.结果 42例患者肝动脉插管直接进入CHL供血血管17例,其余均为进入血管瘤所在的肝段或联合肝段动脉.血管瘤直径5～10 cm者栓塞(1.3±1.1)次/人,10～20 cm者栓塞(2.8±2.2)次/人、21～30 cm者栓塞(3.3±2.3)次/人.术后访问6～18个月,4例瘤体缩小>50%,31例缩小25%～50%,6例缩小≤25%,无明显变化1例.全组患者未出现严重并发症.结论平阳霉素加碘化油经肝动脉栓塞治疗海绵状血管瘤安全有效.

Objective To evaluate the therapeutic effect of Pingyangmycin and lipiodol emulsion（PLE） embolization for cavernous hemangioma of liver（CHL）.Methods We analyzed the clinical data of the 42 cases of the CHL treated by selectively injecting pingyangmycin lipiodol emulsion（PLE）into the supplying artery of tumors,and the patients were followed up after the operation for 6 months to 12 months.Results All the 42 patients were performed successfully with Hepatic artery intubation and 17 of these patients were performed with super selectively sent into the supplying artery of tumors.The embolism times was（1.3±1.1）/person for 5～10 cm CHL,（2.8±2.2）/person for 10～20 cm and（3.3±2.3）/person for 21～30 cm.Followed up 6 months to 18 months,CHL reduced by over 50% in 4 cases,and reduced by 25%~50% in 31 cases,and reduced less than 25% in 6 cases,respectively.But one case didn＇t appear clinical effect.There were no serious complications.Conclusion It is reliable and feasible that treating CHL with PLE through super selective hepatic artery intubation.