HIV/AIDS合并肺结核与单纯肺结核患者临床特征分析

Clinical Characteristics of Pulmonary Tuberculosis Patients with and without HIV(+)/AIDS

目的增强对HIV/AIDS合并肺结核与单纯肺结核患者临床特征的认识.方法收集云南省昆明市第三人民医院2010年1月至2011年1月收治的HIV/AIDS合并肺结核初治患者42例设为A组,同期住院的单纯肺结核患者50例设为B组,两组进行回顾性对照分析.结果 A组与B组比较临床表现中的肺外结核发生率比较差异具有统计学意义(P<0.01),实验室检查中PPD实验、免疫功能,比较差异具有统计学意义(P<0.01).影像学检查A组与B组比较影像学病变范围具有明显统计学差异(P<0.01).结论 HIV/AIDS合并肺结核与单纯肺结核患者临床表现不同,诊断与治疗应综合分析及多样化治疗.

Objective To enhance the cognition about clinical characteristics of pulmonary tuberculosis patients with and without HIV（＋）/AIDS.Methods The Group A was 42 cases of pulmonary tuberculosis patients with HIV（＋）/AIDS,and the GroupB was 50 cases of pulmonary tuberculosis patients without HIV（＋）/AIDS,who were admitted in The Third People＇s Hospital of Kunming from January 2010 to January 2011.A retrospective cohort study was conducted in the two groups.Results There were statistical significant differences between the two groups in the incidence rate of extrapulmonary tuberculosis（χ2=16.745,P=0.01）,the PPD test（χ2=7.068,P=0.008）,the examination of immunocompetence（χ2=77.072,P=0.01）and the examination of imageology（χ2=14.313,P=0.000）.Conclusion The difference between the two groups is obvious in the clinical manifestations,the diagnosis and therapy.